Exposure to fenvalerate and tebuconazole exhibits combined acute toxicity in zebrafish and behavioral abnormalities in larvae

In aquatic ecosystems, pesticide residues meanly present as mixtures of varying complexity, which may lead to compound pollution organisms. Therefore, it is great practical importance evaluate the combined toxic effects pesticides. this study, mixture acute toxicities fenvalerate with tebuconazole on zebrafish larvae and adults were investigated. The toxicity swimming behavior also analyzed. systems showed antagonistic adult when mixing ratios equal, but other two mixes both synergistic effects. strongest effect was observed mixed in ratio 8:2. significantly inhibited after exposure single or for 2 days. However, significant up-regulation behavioral indicators at beginning groups. results that had risk zebrafish. It recommended simultaneous use pesticides agricultural activities near water bodies should be scientifically controlled avoid adverse